Cryptococcal meningitis in a previously healthy child

Clinical Immunophenotype at Disease Onset in Previously Healthy Patients With Cryptococcal Meningitis

Cryptococcal meningitis (CM) is a global disease with significant morbidity and mortality. Although low peripheral blood cluster of differentiation 4 (CD4) cell counts are found to be related to a high burden of cryptococcus in HIV-infected patients, little is known about possible immune defects in previously healthy patients (PHPs). We performed a retrospective study of 41 CM patients treated ...

Ecythema gangrenosum in a previously healthy child

Sum mary Ecthyma gangrenosum is a well known cutaneous manifestation of Pseudomonas aeruginosa infections and is usually seen in immunocompromised patients. A previously healthy 5-month-old boy presented to our hospital with a complaint of an open inguinal wound. Physical examination revealed several ulcers surrounded by erythematous halos in bilateral inguinal regions. Pseudomonas aeruginosa w...

Varicella zoster virus meningitis in a previously immunized child.

We are reporting a previously well 5-year-old child with varicella-zoster meningitis who had a history of a previous immunization against varicella. This child also developed a transient sensorineural hearing loss. The child was treated with acyclovir and made a full recovery.

Cryptococcal Meningitis

Virulence probably plays a relatively small role in the outcome of this infection: the crucial factor is the immune status of the host. The most serious infections usually develop, in fact, in patients with defective cell-mediated immunity, for example those with AIDS, organ transplantation, reticuloendothelial malignancy, corticosteroid treatment and sarcoidosis, but not in subjects with neutr...

Cryptococcal Meningitis in a Horse